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HomeProductsLiquid Sterile FiltrationSterilizing-Grade PES Filters (0.45 μm / 0.2 μm)
Sterilizing-Grade PES Filters (0.45 μm / 0.2 μm)

Sterilizing-Grade PES Filters (0.45 μm / 0.2 μm)

Alioth Alipore® ZHC flters use sterilizing-grade 0.2 µm PES membrane as the fnal fltration layer and construct with double-layer asymmetric PES membrane, which allow for various combinations of membrane pore sizes to meet the requirements for fltration precision in diferent ap-plications. The flters are suitable for a variety of sterile fltration of process fuids. Alipore® ZHC flters are validated by strict fltration perormance guarantees, with wide chemical compatibility, low protein adsorption, high fow rate and high capacity to optimize process efciency and cost efectiveness.

Key Features and Benefits

Double-layer asymmetric PES membrane
High fux and high capacity
Reliable bacterial retention
Low protein absorption
Wide chemical compatibility (pH 1–14)
100% integrity test passed

Typical Applications

Bufer fltration
Culture media fltration
Clarifed cell culture fuid fltration
Intermediate and bulk solution fltration
Final product sterile fltration

产品参数

产品参数

ProductSpecifications10 inch20 inch30 inch
Diameter69 mm69 mm69 mm
Maximum Length318 mm566 mm813 mm
Materials ofConstructionMembraneHydrophilic polyethersulfone (PES)
Supporting LayerPolypropylene (PP)
O-ringsSilicone, Ethylene propylene diene monomer(EPDM), FEP/PFA encapsulated O-rings
Core/Cage/End caps/AdaptorPolypropylene (PP)
Integrity TestingBubble Point≥3520 mbar (51 psi) @ wetted with H2O, 20℃
Diffusion FlowTest pressure 2760 mbar (40 psi) (20℃, compressed air), ≤24 mL/min @10 inch
WorkingCharacteristicsMaximum Differential PressureForward: 7.0 bar（101.5 psi）@ 25°C/3.0 bar（43.5 psi）@ 80°C
Reverse: 3.0 bar（43.5 psi）@ 25°C/1.0 bar (14.5 psi) @ 80℃
Sterilization ResistanceSteam-In-Place: 135℃, 30 min, 50 cycles
Autoclave: 126℃, 60 min, 50 cycles
Effective Filtration Area0.54 m21.08 m21.62 m2
Pore Size0.45+0.2 μm
Bacterial Retention﹥107 cfu/cm2 B. diminuta ( ATCC® 19146TM )
Biological SafetyAll construction components meet the biological safety requirements refering to USP<88> Class VI plastic and USP<87>
Indirect Food AdditiveAll component materials meet the requirements of Indirect Food Additive cited in EU 1935/2004/EC and FDA 21 CFR 177-182
CleanlinessMeets the requirements for a'non-fber releasing' flter defnedin FDA 21 CFR 211.72 and 210.3 (b) (5) (6), and pariculate matter meets the requirements of USP<788>
EndotoxinEndotoxin﹤0.25 EU/mL by LAL test method, which complies with the requirements of USP<85>
TOC / ConductivityTOC﹤0.5 mg/L, Conductivity﹤1.3 μS/cm
Manufacturing Integrity100% integrity test passed
Manufacturing EnvironmentManufactured in conformance with cGMP

Typical Flow Characteristics

Typical Flow Characteristics

Typical Flow Characteristics

订购信息

Format
  • C=Carridge
Membrane material
  • E=PES
Membrane series
  • Z=Z series
Pore size
  • 52=0.45+0.2 μm
Length
  • 1=10 inch
  • 2=20 inch
  • 3=30 inch
Catridge adaptor
  • 7=226, spearhead with fns
O-ring
  • S=Silicone
  • T=EPDM
  • B=FEP/PFA encapsulated O-rings
Package
  • 1=1/PK
  • 3=3/PK (20&30 inch)