
Depth Filtration
Alioth Depth Filtration Series provides efficient and reliable clarification solutions for biopharmaceutical processes.
Depth Filtration Series
As the critical bridge between upstream harvest and downstream purification, it efficiently removes cells, debris, aggregates, HCP, DNA, and endotoxins — creating a clean foundation for chromatography, ultrafiltration, and sterile filtration.
With flexible specifications and media options, the series covers laboratory, pilot, and commercial-scale operations. Core products include Alidep®Depth Filters, Alidep®Depth Stacked Filters, Alicarb®Activated Carbon Series Stacked Filters, single-use connector kits, and needle-depth filters. Key advantages include flexible media selection and proven process compatibility, with successful applications across dozens of clinical Phase III and commercial drug projects — spanning CHO cultures, vaccines, microbial fermentations, plasma products, small molecule APIs, and highly viscous feeds.
Typical Applications
- Clarify mammalian cell culture harvests (primary & secondary).
- Clarify recombinant protein or plasmid fermentations (yeast, E. coli).
- Separate blood products, vaccines, and viscous colloids.
- Remove process impurities (HCP, DNA, endotoxins).
Related Articles
Impurity Adsorption Studies for Alioth Alidep® Depth Filters(II)
The Operation Method of Lab Scale Depth Filter(with Teaching Video Attached)
Can depth filters also retain bacteria?
How to ensure the safety of depth filters?
How to evaluate the performance characterization of depth filtration?
What Physical Characteristics Should Be Considered When Using Depth Filters? – Part II
What Physical Characteristics Should Be Considered When Using Depth Filters? – Part I
How to conduct the selection study of depth filters?
Selection and Scalability of Depth Filters
How do Depth Filters Work?
The Structure of Depth Filters
A comprehensive guide to the Development, Evolution, and Principles of Depth Filtration
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Alidep® Depth Filter Performance Series I: Linear Scale-Up
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Resource Downloads
Alidep® Depth Filter
Alicarb® Activated Carbon Series Stacks.pdf
PDF · 418.22 KB · Published on 2026-05-11
Alidep® Depth Stacked Filter.pdf
PDF · 628.46 KB · Published on 2026-05-11
Alidep® Depth Filter.pdf
PDF · 641.68 KB · Published on 2026-05-11
Alidep® Disc Depth Filter.pdf
PDF · 467.76 KB · Published on 2026-05-11
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