
Recombinant Proteins
Alioth delivers customized pre-filtration and sterile filtration strategies across diverse recombinant protein expression systems, ensuring process flowability and final product purity.
Recombinant Proteins
Recombinant protein drugs, produced through genetic engineering, offer exceptional specificity and proven efficacy in treating cancer, metabolic disorders, and viral infections — making them one of the fastest-growing sectors in pharmaceuticals. The complexity of feed streams from diverse host expression systems poses significant challenges to filtration process compatibility.
Across diverse recombinant protein expression systems, filtration is key to ensuring process robustness. Alioth filtration solutions are widely applied in fermentation broth clarification, sterile filtration of process fluids (culture media, buffers), microbial control of intermediates, and fermentation gas filtration — ensuring target protein purity and sterility assurance throughout the entire process.
Process Flow

Virus Inactivation

Affinity Chromatography

Bioburden Reduction

Secondary Clarification/Depth Filtration

Primary Clarification/Depth Filtration

Clarification/Depth Filtration

Bioburden Reduction

Anion Chromatography

Bioburden Reduction

Cation Chromatography

Formulation &Final Filling
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