Liquid Sterile Filtration

Serving as the final barrier to sterility, liquid sterile filtration physically retains all bacteria, yeast, and mold through absolute pore sizes of 0.2 μm (or smaller) while ensuring complete passage of target proteins — indispensable prior to drug filling and for sterile process fluids. Core products include Alipore^® DHC high-throughput sterile-grade hydrophilic PES filters (0.2+0.2 μm / 0.45+0.2 μm) and Alipore^® DHR high-retention sterile-grade hydrophilic PES filters (0.2+0.1 μm), available in disc, capsule, and cartridge formats from lab to large-scale production. Key advantages include outstanding microbial retention, validated integrity testing, and low protein adsorption. DHC delivers high flow and loading capacity; DHR adds reliable mycoplasma retention. All products comply with USP, FDA, and related pharmacopeial standards with complete E&L documentation. Applications span final sterile filtration of biologics, vaccines, cell/gene therapies, and sterile injectables, as well as sterile processing of culture media, sera, buffers, and bioreactor feeds.