Applications

Applications

We continuously iterate to deliver superior filtration solutions perfectly aligned with your applications.

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Application-Driven R&D

Guided by the philosophy of DbA® "Design by Application", Alioth deeply understands the bioprocess details of upstream and downstream, and starting from the specific needs and filtration challenges of pharmaceutical manufacturers, Alioth continuously develops and iterates filtration products and solutions that deliver superior performance and application fit.

To date, we have accumulated over 1,500 pharmaceutical filtration application cases, spanning antibodies, ADCs, vaccines, blood products, CGT, and small-molecule drugs.

1,500+
Successful cases
10+
Application segments
500+
Customers with repeat orders

Core Application Areas

Deeply understanding the mechanisms behind diverse biopharma processes to deliver targeted, scenario-oriented solutions.

Antibodies & ADCs
mAbs / BsAbs / ADCs

Antibodies & ADCs

Alioth's high-performance depth and sterile filtration solutions address the demands of large-scale antibody and ADC manufacturing — ensuring consistent yield and reliable sterile assurance.

Monoclonal Antibodies (mAbs)Bispecific Antibodies (BsAbs)Antibody-Drug Conjugates (ADCs)
Recombinant Proteins
Expression / Purification

Recombinant Proteins

Alioth delivers customized pre-filtration and sterile filtration strategies across diverse recombinant protein expression systems, ensuring process flowability and final product purity.

Recombinant HormonesCytokines / InterferonsRecombinant EnzymesFusion Proteins
Vaccines
mRNA / Recombinant / VLP

Vaccines

Alioth's sterile-grade filtration solutions safeguard vaccine manufacturing, serving as a critical step for sterility and compliance of the final products.

Inactivated VaccinesLive Attenuated VaccinesRecombinant Subunit VaccinesmRNA VaccinesViral Vector Vaccines
Cell & Gene Therapy (CGT)
CAR-T / Gene Therapy

Cell & Gene Therapy (CGT)

Alioth provides gentle, reliable sterile filtration for high-standard cell and gene therapy manufacturing, protecting the sterility of critical process fluids.

CAR-T / CAR-NK TherapiesAAV Gene TherapyLentiviral / Retroviral VectorsOncolytic Viruses
Plasma
Albumin / Ig / Coagulation Factors

Plasma

Alioth's filtration technology spans plasma separation, purification, and concentration, enhancing process robustness and safeguarding biological product safety and compliance.

AlbuminCoagulation FactorsImmunoglobulins
Small Molecule Drugs
Chemical Pharmaceuticals / API / Formulations

Small Molecule Drugs

For traditional small-molecule drugs with demanding solvent environments and sterility requirements, Alioth offers highly chemically compatible filtration solutions, ensuring drug safety and stability.

InjectablesOral Solid Dosages (OSD)Large Volume Parenterals (LVP)Eye DropsHighly Potent APIs (HPAPIs)
Peptides
Synthesis / Purification

Peptides

To maximize yield of high-value peptide drugs, Alioth's low-adsorption sterile filtration products deliver reliable sterility while minimizing product loss.

Therapeutic Peptides (e.g., GLP-1 Analogues)Antimicrobial Peptides (AMPs)Diagnostic Peptides
Synthetics Biology
Engineered Strains / Enzyme Engineering / Biomanufacturing

Synthetics Biology

Alioth's filtration technology enables efficient separation and concentration of synthetic biology products, providing reliable support for fermentation broth clarification and downstream purification.

Amino AcidsOrganic AcidsNatural Active IngredientsEnzymes
Others
Cosmetics / Food / Molecular Diagnostics

Others

For unique process fluids and filtration challenges, Alioth draws on our comprehensive product portfolio and deep technical support to deliver tailored solutions.

Cosmetic Raw MaterialsFood AdditivesDiagnostic ReagentsCell Culture Media

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