AliothBio
High-Throughput PES Prefilters (0.45 / 0.65 / 0.8 / 1.2 μm)
Alioth Alipore® DPHC monolayer polyethersulfone (PES) prefilters are suitable for a variety of biopharmaceutical industry of process fluids with both cartridge and disposable capsule format available. This filter features validated excellent chemical compatibility, particle removal capabilities, and high throughput characteristics, protecting the sterilizing filter to optimize economic benefits.
Key Features and Benefits
Highly asymmetric monolayer PES membrane
High flux and high capacity
Removal of particulate impurities
Wide chemical compatibility (pH1-14)
Typical Applications
Buffers
Protective filtration before critical purification process
Bacteria reduction filtration process for biological products
Product Specifications
Alicap® Capsule Filters
| Product Specifications | L5 | L10 | L20 | L30 | T10 | T20 | T30 | |
| Body Diameter | 92 mm | 92 mm | 92 mm | 92 mm | 92 mm | 92 mm | 92 mm | |
| Maximum Width | 132 mm | 132 mm | 132 mm | 132 mm | 132 mm | 132 mm | 132 mm | |
| Maximum Length | 211 mm | 330 mm | 575 mm | 830 mm | 350 mm | 596 mm | 851 mm | |
| Materials of Construction | Membrane | Hydrophilic polyethersulfone (PES) | ||||||
| Supporting Layer | Polypropylene (PP) | |||||||
| O-rings | Silicone | |||||||
| Core/Cage/End caps/Housing | Polypropylene (PP) | |||||||
| Working Characteristics | Maximum Differential Pressure | Forward: 7.0 bar（101.5 psi）@ 25°C/3.0 bar（43.5 psi）@ 80℃; Reverse: 3.0 bar（43.5 psi）@ 25°C/1.0 bar（14.5 psi）@ 80℃ | ||||||
| Sterilization Resistance | Autoclave(A&G): 131℃, 30 min, 15 cycles Gamma-compatible (G): 45 kGy *Capsule filters can't be sterilized by SIP, sterile type capsule filters can't be sterilized again | |||||||
| Effective Filtration Area(Single layer) | 0.32 m2 | 0.65 m2 | 1.30 m2 | 1.95 m2 | 0.65 m2 | 1.30 m2 | 1.95 m2 | |
| Effective Filtration Area(Double layer) | 0.28 m2 | 0.55 m2 | 1.10 m2 | 1.65 m2 | 0.55 m2 | 1.10 m2 | 1.65 m2 | |
| Pore Size | 0.45 μm、0.65 μm、0.8 μm、1.2 μm (Supports arbitrary combinations of dual-layer pore sizes as specified above) | |||||||
| Biological Safety | All construction components meet the biological safety requirements refering to USP<88> Class VI plastic and USP<87> | |||||||
| Indirect Food Additive | All component materials meet the requirements of Indirect Food Additive cited in EU 1935/2004/EC and FDA 21 CFR 177-182 | |||||||
| Cleanliness | Meets the requirements for a 'non-fiber releasing' filter defined in FDA 21 CFR 211.72 and 210.3 (b) (5) (6), and particulate matter meets the requirements of USP<788> | |||||||
| Endotoxin | Endotoxin﹤0.25 EU/mL by LAL test method, which complies with the requirements of USP<85> | |||||||
| TOC/Conductivity | TOC﹤0.5 mg/L, Conductivity﹤1.3 μS/cm | |||||||
| Manufacturing Integrity | 100% integrity test passed | |||||||
| Manufacturing Environment | Manufactured in conformance with cGMP | |||||||
Cartridge Filters
| Product Specifications | 5 inch | 10 inch | 20 inch | 30 inch | |
| Diameter | 69 mm | 69 mm | 69 mm | 69 mm | |
| Maximum Length | 155 mm | 318 mm | 566 mm | 813 mm | |
| Materials of Construction | Membrane | Hydrophilic polyethersulfone (PES) | |||
| Supporting Layer | Polypropylene (PP) | ||||
| O-rings | Silicone, Ethylene propylene diene monomer(EPDM), FEP/PFA encapsulated O-rings | ||||
| Core/Cage/End caps/Adaptor | Polypropylene (PP) | ||||
| Working Characteristics | Maximum Differential Pressure | Forward: 7.0 bar（101.5 psi）@ 25°C/3.0 bar（43.5 psi）@ 80°C Reverse: 3.0 bar（43.5psi）@ 25°C/1.0 bar (14.5 psi) @ 80℃ | |||
| Sterilization Resistance | Steam-In-Place: 135℃, 30 min, 50 cycles Autoclave: 135℃, 30 min, 50 cycles | ||||
| Effective Filtration Area | 0.32 m2 | 0.65 m2 | 1.30 m2 | 1.95 m2 | |
| Pore Size | 0.45 μm、0.65 μm、0.8 μm、1.2 μm (Supports arbitrary combinations of dual-layer pore sizes as specified above) | ||||
| Biological Safety | All construction components meet the biological safety requirements refering to USP<88> Class VI plastic and USP<87> | ||||
| Indirect Food Additive | All component materials meet the requirements of Indirect Food Additive cited in EU 1935/2004/EC and FDA 21 CFR 177-182 | ||||
| Cleanliness | Meets the requirements for a 'non-fiber releasing' filter defined in FDA 21 CFR 211.72 and 210.3 (b) (5) (6), and particulate matter meets the requirements of USP<788> | ||||
| Endotoxin | Endotoxin﹤0.25 EU/mL by LAL test method, which complies with the requirements of USP<85> | ||||
| TOC/Conductivity | TOC﹤0.5 mg/L, Conductivity﹤1.3 μS/cm | ||||
| Manufacturing Integrity | 100% integrity test passed | ||||
| Manufacturing Environment | Manufactured in conformance with cGMP | ||||
Typical Flow Characteristics
Water Flow Rate and Pressure Drop-Alipore® DPHC 0.65+0.45 μm Cartridge Filters
Ordering Information - Alicap® Capsule Filters
Pore Size: Single layer: 0.45 μm, 0.65 μm, 0.8 μm, and 1.2 μm. Double layer: Support arbitrary combinations of pore sizes from the above specifications. Connector: Alicap® L5/L10/L20/L30, available with B4, T1 Connector; Alicap® T10/T20/T30, available with T1 Connector.
Format
- K=L-type Capsule
- T=T-type Capsule
Membrane material
- E=PES
Membrane series
- D=D series
Pore size
- 04=0.45 μm
- 06=0.65 μm
- 08=0.8 μm
- 1U=1.2 μm
Length
- 5: Alicap® L5
- 1: Alicap® L10
- 2: Alicap® L20
- 3: Alicap® L30
Capsule connector
- T1: 38 mm(1 1/2") Sanitary flange inlet and outlet
- B4: 13 mm(1/2") Single-stage hose inlet and outlet
O-ring
- S=Silicone
Package
- 1=1/PK
Sterilization
- A=Autoclavable
- G=Gamma compatible
- S=Sterile
Ordering Information - Cartridge Filters
Pore Size: Single layer: 0.45 μm, 0.65 μm, 0.8 μm, and 1.2 μm. Double layer: Support arbitrary combinations of pore sizes from the above specifications.
Format
- C=Cartridge
Membrane material
- E=PES
Membrane series
- D=D series
Pore size
- 04=0.45 μm
- 06=0.65 μm
- 08=0.8 μm
- 1U=1.2 μm
Length
- 5=5 inch
- 1=10 inch
- 2=20 inch
- 3=30 inch
Catridge adaptor
- 7=226, Spearhead with fins
- 2=226, Flat end with fins(5 inch)
O-ring
- S=Silicone
- T=EPDM
- B=FEP/PFA encapsulated O-rings
Package
- 1=1/PK
- 3=3/PK(20&30 inch)
订购信息 4
Format
Resource Downloads
Alipore® DPHC High-Throughput Hydrophilic PES Prefilter.pdf
PDF · 3.94 MB · Published on 2026-05-11
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